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Table 2 Immunohistochemical Results in GIST

From: Cyclin H expression is increased in GIST with very-highrisk of malignancy

Immunohistochemistry

Positive, n (%)

Negative, n (%)

Total, n

c-kit (CD117)

92

(98%)

2

(2%)

94

cyclin H

23

(24%)

72

(76%)

95

CD34

63

(85%)

11

(15%)

74

smooth muscle actin

11

(17%)

53

(83%)

64

desmin

4

(9%)

43

(91%)

47

vimentin

32

(100%)

0

(0%)

32

NSE

6

(55%)

5

(45%)

11

S100

0

(0%)

55

(100%)

55

  1. Two c-kit negative GIST turned to be PDGFRα positive, confirmed as GIST by mutational analysis