Table 1 Claudin-3 and -4 mRNA and protein expression in primary ovarian cancer cell lines
Cell line | Patient characteristics | Flow cytometry | rtPCR | |||
|---|---|---|---|---|---|---|
| Â | Histology | Stage | Claudin-3/4 | Claudin-3/4 | Claudin-3 | Claudin-4 |
| Â | Â | Â | MFI* + SD | Cells (%) | mRNA copy # | mRNA copy # |
NOVA** |  |  | 11.2 ± 3.4 | 5 | 1 | 1 |
VERO cells |  |  | 86.8 ± 10.5 | 100 | - | - |
OSPC-ARK-1 | OSPC*** | IV | 118.8 ± 12.5 | 100 | 6654 | 2372 |
OSPC-ARK-2 | OSPC | IIIC | 58.7 ± 6.1 | 100 | 4124 | 962 |
OSPC-ARK-3 | OSPC | IIIA | 89.8 ± 8.7 | 100 | 31129 | 330 |
OSPC-ARK-4 | OSPC | IV | 45.9 ± 16.2 | 100 | 37122 | 140 |
OSPC-ARK-5 | OSPC | IV | 102.7 ± 11.3 | 100 | 9108 | 6418 |
CC-ARK-1 | CC**** | IIIC | 108.3 ± 8.7 | 100 | 7559 | 325 |
CC-ARK-2 | CC | IC | 105.7 ± 10.2 | 100 | 10141 | 2055 |