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Table 1 Claudin-3 and -4 mRNA and protein expression in primary ovarian cancer cell lines

From: Clostridium perfringens enterotoxin carboxy-terminal fragment is a novel tumor-homing peptide for human ovarian cancer

Cell line Patient characteristics Flow cytometry rtPCR
  Histology Stage Claudin-3/4 Claudin-3/4 Claudin-3 Claudin-4
    MFI* + SD Cells (%) mRNA copy # mRNA copy #
NOVA**    11.2 ± 3.4 5 1 1
VERO cells    86.8 ± 10.5 100 - -
OSPC-ARK-1 OSPC*** IV 118.8 ± 12.5 100 6654 2372
OSPC-ARK-2 OSPC IIIC 58.7 ± 6.1 100 4124 962
OSPC-ARK-3 OSPC IIIA 89.8 ± 8.7 100 31129 330
OSPC-ARK-4 OSPC IV 45.9 ± 16.2 100 37122 140
OSPC-ARK-5 OSPC IV 102.7 ± 11.3 100 9108 6418
CC-ARK-1 CC**** IIIC 108.3 ± 8.7 100 7559 325
CC-ARK-2 CC IC 105.7 ± 10.2 100 10141 2055
  1. *MFI: Mean Fluorescence Intensity
  2. **NOVA: Normal Ovarian control cells
  3. ***OSPC: Ovarian Serous Papillary Carcinoma
  4. ****CC: Clear Cell ovarian carcinoma