Variable | Single-variate analyses | Multivariate analysis | ||||
---|---|---|---|---|---|---|
Crude HR | 95% CI | P value | AHR | 95% CI | P value | |
25OHD, ng/mL | 0.98 | 0.93-1.02 | 0.31 | 0.91 | 0.84-0.99 | 0.027 |
Age at surgery, years | 1.01 | 0.98-1.04 | 0.49 | 1.07 | 1.03-1.12 | 0.002 |
Gender, female | 1.26 | 0.66-2.41 | 0.49 | 1.59 | 0.49-5.15 | 0.44 |
Time period of surgery | ||||||
May 2003 - December 2005 | 0.94 | 0.48-1.85 | 0.87 | 0.41 | 0.13-1.27 | 0.12 |
January 2006 - January 2008 | reference | |||||
Stage | ||||||
Stage I | 0.00 | - | - | 0.00 | - | - |
Stage II | 0.02 | 0.01-4.32 | < 0.001 | 0.02 | 0.02-1.74 | 0.13 |
Stage III | 0.13 | 0.07-0.27 | < 0.001 | 1.13 | 0.16-7.85 | 0.90 |
Stage IV | Reference | Reference | ||||
Location of tumor | ||||||
Proximal colon | 1.07 | 0.52-2.22 | 0.86 | 1.42 | 0.55-3.68 | 0.47 |
Distal colon | 0.45 | 0.15-1.34 | 0.15 | 0.42 | 0.09-1.94 | 0.27 |
Rectum | Reference | Reference | ||||
Type of resection, % | ||||||
R0 | 0.04 | 0.02-0.09 | < 0.001 | 0.01 | 0.00-0.11 | < 0.001 |
R1 | 1.04 | 0.48-2.26 | 0.92 | 0.44 | 0.11-1.78 | 0.25 |
R2 | Reference | Reference | ||||
Adjuvant chemotherapy | 6.06 | 2.15-17.10 | 0.001 | 0.75 | 0.17-3.34 | 0.71 |
Number of lymph nodes with metastasis*2 | 1.08 | 1.05-1.11 | < 0.001 | 1.09 | 1.02-1.16 | 0.016 |