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Table 6 DLBCL (ABC/GCB) subtypes by clinical presentation, viral (HIV/EBV) status, IHC (Ki-67 and BCL-2) and DNA ploidy at MNH (1996-2006)

From: Tanzanian malignant lymphomas: WHO classification, presentation, ploidy, proliferation and HIV/EBV association

Subtypes
[No. (%)]
Sex Age-group Clinical Presentation
in relation to the diaphragm
HIV status Ki-67 reactivity EBER ISH reactivity DNA Ploidy BCL2/Mum1p
subtype
Total [No. (%)]
  M F ≤18 >18 Supra- Sub- Gen Pos Neg Low High Pos Neg nd Diploid Aneuploid Grp. 1 Grp. 2 No.(%)
ABC 9 (50.0) 6 (66.7) 0 15 (65.2) 9 (66.7) 4 (80.0) 4 (50.0) 2 (40.0) 1 (33.3) 11 (61.1) 4 (44.4) 5 (50.0) 8 (53.3) 2 6 (66.7) 9 (50.0) 7 (36.8) 8 15 (55.6)
GCB 9 (50.0) 3 (33.3) 3 8 (34.8) 3 (33.3) 1 (20.0) 4 (50.0) 3 (60.0) 2 (66.7) 7 (38.9) 5 (55.6) 5 (50.0) 7 (46.7) 0 3 (33.3) 9 (50.0) 12 (63.2) 0 12 (44.4)
Total 18 (66.7) 9 (33.3) 3 (11.1) 23 (88.9) 12 (44.4) 5 (18.5) 8 (29.6) 5 (62.5) 3 (37.5) 18 (66.7) 9 (33.3) 10 (37.0) 15 (55.5) 2 (7.4) 9 (33.3) 18 (66.7) 19 (70.0) 8 (30.0) 27* (100.0)
  1. *This is the total number of DLBCLs analyzed by FACS for DNA Ploidy
  2. nd = not determined
  3. ABC = activated B-cell like DLBCL, GCB = germinal center B-cell like DLBCL
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