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Figure 1 | BMC Cancer

Figure 1

From: Modulation of mdm2 pre-mRNA splicing by 9-aminoacridine-PNA (peptide nucleic acid) conjugates targeting intron-exon junctions

Figure 1

The MDM2 gene and PNA target positions. (A) The regions of mdm2 pre-mRNA used as targets for PNAs are indicated with thick bars under the exons ((a), (b) and (c)). Numbered boxes: exons; lines: introns. (B) The exact sequence position of PNAs targeted to the 5'-splice site of intron2 (a), 3'-splice site of intron2 (b) and 3'-splice site of intron3 (c) are shown. Intron sequences are in lower case.

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