Figure 2From: Cardiotoxicity of anthracycline agents for the treatment of cancer: Systematic review and meta-analysis of randomised controlled trials Clinical cardiotoxicity defined as incidence of CHF in RCTs comparing different treatment regimens. The open diamond represents the pooled Peto Odds Ratio and 95% confidence interval (CI) for each treatment comparison. I-squared represents the proportion of variability between studies in excess of that expected due to chance, and p = probability that differences between study estimates are due to chance.Back to article page