Table 1 Clinico-pathologic characteristics and MED28 expression in individuals with breast cancer

Age at Diagnosis

= 55.2

= 55.9

0.8926^a

ρ = 0.024^b

0.8195^b

   Median (Range)

53 (30 - 89)

53.5 (30 - 89)

52 (36 - 89)

   25th to 75th Quartile

45 - 66

45 - 74

45 - 77.2

Clinical Stage

= 1.712

= 2.318

0.0035^a

0.0052^b

   I

33

28

5

0.0028^d

0.782 ± 0.721

0.0090^e

   II

36

30

6

0.918 ± 0.541

   III

17

7

10

1.312 ± 0.708

   IV

2

1

1

1.075 ± 0.813

Tumor Grade

= 2.063

= 2.455

0.0678^a

0.0061^b

   1

23

21

2

0.0882^d

0.598 ± 0.429

0.0099^f

   2

25

17

8

1.009 ± 0.698

   3

37

25

12

1.112 ± 0.726

   Unknown

3

3

0

Lymph Node Metastasis

0.1004^c

0.0303^a

   Absent

38

32

6

0.833 ± 0.775

   Present

34

22

12

1.083 ± 0.612

   Unknown^†

16

12

4

Tumor Size (cm)

= 2.175

= 2.955

0.0283^a

ρ = 0.303^b

0.0060^b

   Median (Range)

2.2 (0.1 - 9.0)

2.0 (0.1 - 7.25)

2.5 (0.5 - 9.0)

   25th to 75th Quartile

1.18 - 3.00

1.0 - 2.5

1.7 - 4.0

Lymphovascular Invasion

0.0720^c

0.0201^a

   Absent

55

45

10

0.812 ± 0.599

   Present

32

20

12

1.177 ± 0.734

   Unknown

1

1

0

ER Status

0.2514^c

0.0489^a

   Positive

62

48

14

0.866 ± 0.594

   Negative

21

13

8

1.271 ± 0.822

   Unknown

5

5

0

PR Status

0.0640^c

0.1828^a

   Positive

58

47

11

0.864 ± 0.562

   Negative

28

17

11

1.142 ± 0.838

   Unknown

2

2

0

HER-2/neu Status

0.0335^c

0.1022^a

   Positive

19

10

9

1.181 ± 0.644

   Negative

61

49

12

0.923 ± 0.661

   Unknown

8

7

1