MED28 expression by histology. MED28 expression as classified by different TMA spot-level histologies. The columns show the mean integrated cytoplasmic expression of MED28; bars, SE. MED28 expression in DCIS, IDC, and metastatic lesions were significantly elevated compared to either normal or DH tissues (P < 0.0001). MED28 expression in DCIS lesions was also slightly different from expression in metastatic lesions (P = 0.040). n is the number of spots in each category.