Figure 7
From: EpCAM nuclear localization identifies aggressive Thyroid Cancer and is a marker for poor prognosis
Kaplan-Meier estimation of cumulative proportion of overall survival: (A) Nuclear Ep-ICD accumulation in thyroid cancers correlated significantly with reduced overall survival (OS) of these patients (p < 0.0004). The median OS was 5 months in the group of patients showing nuclear Ep-ICD as compared to 198 months for patients who did not have detectable nuclear Ep-ICD. (B) Loss of membranous EpEx expression was also associated with reduced overall survival (OS) for patients. The patients showing loss of membranous EpEx had shorter OS (median = 5months) than those showing membranous expression (median = 198 months, p < 0.0004).