Table 4 Comparative summary and main findings of prostate viral infection reports

Sweden/201 prostate tissue

samples from patients with

BPH that later progressed to

PC and 201 matched controls

that did not.

There were no differences in

the prevalence of adenovirus,

herpesvirus, papillomavirus, polyoma

virus and C. albicans DNA.

Bergh J.

British

Journal of

Cancer 2007.

Baltimore, USA/30 PC

subjects for bacterial DNA

and 200 PC cases for

viral-parasite

DNA detection.

Most prostatectomies (87%)

contain bacterial DNA from

one or more species. The

majority of individual tissue

core samples were negative,

suggesting regional heterogeneity

in the presence of bacteria

and a lack of a generalized

or ubiquitous prostatic flora.

Sfanos KS.

The Prostate

2008.

Greece/42 samples

of prostatic

malignancies.

BKV was frequently detected

and could play a relevant role

in the development and

progression of human PC,

whereas HPV does not seem

to be implicated in this type of

human neoplasia.

Balis V.

Int J Biol

Markers. 2007.

LongBeach, USA/

12 PC Fresh frozen

tissues and 20

paraffin-embedded

archival samples.

The prostate is a complex

habitat where mixed

infections with oncogenic

DNA viruses frequently

occur and opens the

discussion to the

potential role of these

viruses in the PC.

Zambrano A,

Prostate

2002.

Monterrey,

Mexico/55

Cases of PC

and 75 Controls.

HPV frequency was

significantly higher in PC

cases than in controls;

this finding suggests

their participation in

PC develpment or tumor progression.

This work.