Skip to main content

Table 4 Comparative summary and main findings of prostate viral infection reports

From: Identification of viral infections in the prostate and evaluation of their association with cancer

Country/Study
Description
Pathogen Samples (+) Total Findings Reference
Sweden/201 prostate tissue
samples from patients with
BPH that later progressed to
PC and 201 matched controls
that did not.
Epstein-Barr Virus.
JCV.
BKV, HPVs, CMV.
Adenovirus, HSV1 and 2
C.albicans.
31
10
0
0
2
43
(352)
There were no differences in
the prevalence of adenovirus,
herpesvirus, papillomavirus, polyoma
virus and C. albicans DNA.
Bergh J.
British
Journal of
Cancer 2007.
Baltimore, USA/30 PC
subjects for bacterial DNA
and 200 PC cases for
viral-parasite
DNA detection.
BKV.
Chlamydia T.
CMV.
Epstein-Barr Virus.
HPVs, XMRV.
1
1
1
16
0
18
(200)
Most prostatectomies (87%)
contain bacterial DNA from
one or more species. The
majority of individual tissue
core samples were negative,
suggesting regional heterogeneity
in the presence of bacteria
and a lack of a generalized
or ubiquitous prostatic flora.
Sfanos KS.
The Prostate
2008.
Greece/42 samples
of prostatic
malignancies.
BKV.
JCV.
HPVs..
8
0
2
10
(42)
BKV was frequently detected
and could play a relevant role
in the development and
progression of human PC,
whereas HPV does not seem
to be implicated in this type of
human neoplasia.
Balis V.
Int J Biol
Markers. 2007.
LongBeach, USA/
12 PC Fresh frozen
tissues and 20
paraffin-embedded
archival samples.
HPVs.
JCV.
BKV.
0 (20), 6 (12)
10 (20),6 (12)
0 (20), 3 (12)
10 (20)
And
7(12)
The prostate is a complex
habitat where mixed
infections with oncogenic
DNA viruses frequently
occur and opens the
discussion to the
potential role of these
viruses in the PC.
Zambrano A,
Prostate
2002.
Monterrey,
Mexico/55
Cases of PC
and 75 Controls.
JCV, BKV, SV40.
HPVs.
HCMV.
XMRV.
0
15
6
1
22
(130)
HPV frequency was
significantly higher in PC
cases than in controls;
this finding suggests
their participation in
PC develpment or tumor progression.
This work.