Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer

Table 2 Results of Cox Regression Analysis.

Factor	Hazard Ratio	95% CI	p
Islet TNFα	0.995*	0.989 to 1.000	0.048†
Stromal TNFα	1.006*	1.002 to 1.011	0.007†
Age	1.022	1.000 to 1.043	0.049†
Pathological stage			0.002†
I	1.000
II	0.283‡	0.077 to 1.035	0.056
IIIa	0.373	0.102 to 1.372	0.138
IIIb and IV	0.712	0.194 to 2.619	0.609
Grade - differentiated			0.078†
Well	1.000
Moderate	0.481§	0.177 to 1.306	0.151
Poor	0.752	0.488 to 1.159	0.197
Histology			0.711
Squamous	1.000
Adenocarcinoma	0.708	0.323 to 1.553	0.389
Large	0.828	0.363 to 1.891	0.654
Other NSCLC	0.621	0.235 to 1.640	0.336

*Continuous variable used. For every increase of 1 in the value of the variable, the hazard increases by the value of the hazard ratio.
† Overall significance as a prognostic factor
‡ Hazard relative to stage I
§ Hazard relative to well differentiated
¶ Hazard relative to squamous

ISSN: 1471-2407