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Table 2 Results of Cox Regression Analysis.

From: Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer

Factor Hazard Ratio 95% CI p
Islet TNFα 0.995* 0.989 to 1.000 0.048†
Stromal TNFα 1.006* 1.002 to 1.011 0.007†
Age 1.022 1.000 to 1.043 0.049†
Pathological stage    0.002†
   I 1.000   
   II 0.283‡ 0.077 to 1.035 0.056
   IIIa 0.373 0.102 to 1.372 0.138
   IIIb and IV 0.712 0.194 to 2.619 0.609
Grade - differentiated    0.078†
   Well 1.000   
   Moderate 0.481§ 0.177 to 1.306 0.151
   Poor 0.752 0.488 to 1.159 0.197
Histology    0.711
   Squamous 1.000   
   Adenocarcinoma 0.708 0.323 to 1.553 0.389
   Large 0.828 0.363 to 1.891 0.654
   Other NSCLC 0.621 0.235 to 1.640 0.336
  1. *Continuous variable used. For every increase of 1 in the value of the variable, the hazard increases by the value of the hazard ratio.
  2. † Overall significance as a prognostic factor
  3. ‡ Hazard relative to stage I
  4. § Hazard relative to well differentiated
  5. ¶ Hazard relative to squamous
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