Figure 5From: Promoter methylation of CDKN2A and lack of p16 expression characterize patients with hepatocellular carcinoma Immunohistochemical expression of p16 in non-tumor liver sample. The non-neoplastic liver tissue shows strong immunostaining for p16 in the ductular reactions and mild cytoplasmic immunostaining in few periportal hepatocytes. Anti-p16-antibody. Hematoxylin-counterstain.Back to article page