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Figure 7 | BMC Cancer

Figure 7

From: Activation of endogenous p53 by combined p19Arf gene transfer and nutlin-3 drug treatment modalities in the murine cell lines B16 and C6

Figure 7

pCLPGp19 gene transfer presensitizes cells to subsequent drug treatment as measured by an MTT cell viability assay. B16 (A) or C6 cells (B) were transduced with equal quantities of pCLPG (diamonds), pCLPGeGFP (squares) or pCLPGp19 (triangles), replated in 96-well plates and quadruplicate samples were treated with drug as indicated for 48 hours before cell viability was assessed by MTT staining. The MTT absorbance observed in cells transduced with pCLPG, but without drug treatment, was used to normalize the values. Results represent the average and standard deviation of three independent experiments.

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