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Figure 10 | BMC Cancer

Figure 10

From: Activation of endogenous p53 by combined p19Arf gene transfer and nutlin-3 drug treatment modalities in the murine cell lines B16 and C6

Figure 10

Decreased proliferation, as revealed by BrdU incorporation, was associated with double treatment conditions. Prior to sacrifice, animals were injected i.p. with a solution of BrdU. Paraffin embedded sections of tumors were probed with an anti-BrdU antibody conjugated to alkaline phosphatase and revealed through a peroxidase reaction.

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