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Table 3 Isoform-specific expression levels of candidate genes in non-malignant and prostate cancer tissues.

From: Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer

Gene

Total Expression in non-malignant prostate tissues

Total Expression in prostate cancer tissues

value

MSMB1

1.8 (6.9)

16.2 (85.2)

4 × 10 -4

MSMB2

125.3 (409.8)

0.6 (4.73)

5.8 × 10 -5

HNF1B(A)

1.2 (2.7)

0.94(1.52)

0.66

HNF1B(B)

5.1 (6.8)

35.1 (52.3)

1.7 × 10 -7

HNF1B(C)

51.8 (109.9)

12 (3.4)

3.9 × 10 -8

CTBP2(1)

1.3 (1.11)

0.62 (0.6)

0.009

CTBP2(3)

0.62 (0.55)

0.45 (0.58)

0.127

CTBP2(4)

1.4 (0.86)

0.70 (0.73)

0.007

  1. Gene expression levels are analysed relative to the beta 2 microglobulin (B2M) and beta glucorinidase (GUSB) genes, and normalised to the average value in the non-malignant samples. The interquartile range is given in parentheses. A P value of 0.006 (P = 0.05/n° of tests) was taken to indicate statistical significance following correction for multiple testing (8 independent tests). Statistically significant results are indicated in bold italic type.