Peri-operative chemotherapy for the treatment of resectable liver metastases from colorectal cancer: A systematic review and meta-analysis of randomized trials

Table 5 Recurrence - free survival (RFS)

	Nordlinger	Lorenz	Portier	Langer	Kemeny	Rudroff	Lygidakis	Wagman
Median RFS time (months)
Chemotherapy	18.7	21.6	24.4	39	-	-	-	30.7
Control	11.7	24.0	17.6	20	-	-	-	8.7
RFS at last follow-up (cumulative %)
Chemotherapy	35.4	33.3	33.5	45	45.7	15	100	-
Control	28.1	36.7	26.7	35	25.2	23	55	-
Hazard Ratio/RR	0.79³	0.95²	0.66³	0.78³	0.56¹	1.12¹	0.6²	0.2²
SE	0.13	0.13	0.19	0.27	0.3	0.42	0.18	0.89
P value	0.058	0.72	0.028	0.35	0.04	0.79	< 0.001	0.03

ISSN: 1471-2407