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Figure 1 | BMC Cancer

Figure 1

From: SMAD4 - Molecular gladiator of the TGF-β signaling is trampled upon by mutational insufficiency in colorectal carcinoma of Kashmiri population: an analysis with relation to KRASproto-oncogene

Figure 1

Partial nucleotide sequence representing the mutant (Above) and normal (Below) {Shown by asterik and arrows}, of MCR region of SMAD4 gene. 1A: Transition of G > A at codon 341; GGT > GAT; Gly > Asp in Exon8 of SMAD4 gene. 1B: Transition of G > A at codon 361; CGC > CAC; Arg > His in Exon8 of SMAD4 gene. 1C: Transversion of T > G at codon 362; TTT > TTG; Phe > Leu in Exon8 of SMAD4 gene. 1D: Transition of G > A at Codon 415; AGA > AAA; Arg > Lys in Exon9 of SMAD4 gene1E: Transversion of T > G at codon 419; TGG > GGG; Trp > Gly in Exon9 of SMAD4 gene

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