Table 4 Determinants of overall survival after BCNU treatment of recurrent glioblastoma (n = 34, 30 events)

Age (years)

≤ 53 vs. > 53 (the median)

0.56

0.22-1.45

0.233

Tumor size (mm²)

≤ 736 vs. > 736 (the median)

0.61

0.22-1.71

0.349

not measurable vs. > 736

0.55

0.18-1.66

0.287

Karnofsky performance score

≤ 70 vs. 80 or 90

1.24

0.50-3.07

0.648

Surgery

Complete resection vs. biopsy/partial resection

3.03

1.05-8.74

0.040

Pre-treatment with temozolomide

yes vs. no

0.81

0.31-2.13

0.674

Previous relapses

1 vs. more than 1

1.81

0.51-6.48

0.357