Table 3 Determinants of progression-free survival after BCNU treatment of recurrent glioblastoma (n = 34, 30 events)

Age (years)

≤ 53 vs. > 53 (the median)

1.12

0.41-2.98

0.844

Tumor size (mm²)

≤ 736 vs. > 736 (the median)

0.46

0.15-1.42

0.177

not measurable vs. > 736

0.45

0.16-1.28

0.135

Karnofsky performance score

≤ 70 vs. 80 or 90

0.50

0.20-1.26

0.143

Surgery

Complete resection vs. biopsy/partial resection

3.11

1.02-9.52

0.047

Pre-treatment with temozolomide

yes vs. no

1.30

0.43-3.91

0.641

Previous relapses

1 vs. more than 1

0.48

0.14-1.61

0.232