From: BCNU for recurrent glioblastoma multiforme: efficacy, toxicity and prognostic factors
Sex | |||
---|---|---|---|
 | Male | 21 | (60%) |
 | Female | 14 | (40%) |
Age, years | |||
 | Median | 53 |  |
 | Range | 27-77 |  |
 | < = 45 | 9 | (26%) |
 | > 45 | 27 | (74%) |
Tumor burden (product of largest cross-sectional diameters), mm2 | |||
 | Median | 736 |  |
 | Range | 20-3519 |  |
 | Not measurable | n = 8 | (23%) |
KPS | |||
 | Median | 70 |  |
 | Range | 40-90 |  |
 | 90 | 7 | (20%) |
 | 70-80 | 15 | (43%) |
 | <70 | 13 | (37%) |
Time from diagnosis to start of BCNU, weeks | |||
 | Median | 38 weeks |  |
 | Range | 11-189 weeks |  |
Primary therapy | |||
 | Total resection | 15 | (43%) |
 | Partial resection | 4 | (11%) |
 | Biopsy | 16 | (46%) |
 | Temozolomide | 24 | (71%) |
 | Radiation | 31 | (89%) |
Number of relapses at start of BCNU therapy | |||
 | First | 30 | (86%) |
 | Second | 4 | (11%) |
 | Third | 0 | (0%) |
 | Fourth | 1 | (3%) |