Skip to main content

Table 1 Correlations of LVD with clinicopathological parameters and VEGFs expressions

From: Different significance between intratumoral and peritumoral lymphatic vessel density in gastric cancer: a retrospective study of 123 cases

Factors

N

I-LVD

P-LVD

  

mean ± SD

P

mean ± SD

P

Tumor differentiation

  

0.802

 

0.739

   High differentiated

11

8.18 ± 2.44

 

12.07 ± 4.49

 

   Mederately/poor differentiated

112

8.00 ± 2.27

 

12.46 ± 3.60

 

Tumor size

  

<0.001

 

<0.001

   <3.2 cm

57

8.93 ± 2.34

 

11.18 ± 3.80

 

   ≥ 3.2 cm

66

7.23 ± 1.91

 

13.50 ± 3.21

 

Depth of invasion

  

0.433

 

0.026

   pT1-2

69

8.16 ± 2.51

 

11.78 ± 3.52

 

   pT3-4

54

7.83 ± 1.96

 

13.26 ± 3.71

 

Lymph node metastasis

  

0.056*

 

<0.001

   Negative

57

8.47 ± 2.27

 

10.50 ± 3.42

 

   Positive

66

7.65 ± 2.24

 

13.98 ± 3.10

 

LVI

  

0.700

 

<0.001

   Negative

83

8.08 ± 2.33

 

11.23 ± 3.29

 

   Positive

40

7.91 ± 2.22

 

14.36 ± 3.44

 

VI

  

0.905

 

<0.001

   Negative

86

8.00 ± 2.38

 

11.65 ± 3.81

 

   Positive

37

8.05 ± 2.67

 

14.24 ± 2.53

 

TNM stage

  

0.067

 

<0.001

   I - II

71

8.34 ± 2.42

 

11.33 ± 3.29

 

   III - IV

52

7.58 ± 2.01

 

13.92 ± 3.66

 

VEGF-A expression

  

0.527

 

0.091

   Low

44

7.84 ± 2.51

 

11.68 ± 3.54

 

   High

79

8.26 ± 2.21

 

12.84 ± 3.69

 

VEGF-C expression

  

0.092*

 

0.003

   Low

42

7.55 ± 2.37

 

11.06 ± 3.26

 

   High

81

8.00 ± 2.34

 

13.13 ± 3.69

 

VEGF-D expression

  

0.514

 

0.005

   Low

72

7.90 ± 2.47

 

11.65 ± 3.44

 

   High

51

8.18 ± 1.99

 

13.53 ± 3.73

 
  1. P, t test; P*, Mann-Whitney U Test. Abbreviation: LVD: lymphatic vessel density; LVI: lymphatic vessel invasion. VI: venous invasion.