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Figure 3 | BMC Cancer

Figure 3

From: Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by Methyl-CpG binding proteins and histone modifications

Figure 3

Protein expression of MBD1, MBD2 and MeCP2 in basal and stimulated MCF-7 cells and in MBD1 -/- mouse embryonic fibroblasts. The MBD protein levels in basal, 5-aza-CdR-, TSA- and 5-aza-CdR&TSA- stimulated MCF-7 cells were evaluated by Western Blot analysis using antibodies specific for MBD1 (60 kDa), MBD2 (49 kDa), MeCP2 (70 kDa) and HSC70 (70 kDa, loading control) (A). The MBD1 protein level in MBD1-/- mouse embryonic fibroblasts was evaluated in comparison to basal MCF-7 cells with antibodies specific for MBD1 (60 kDa) and HSC70 (70 kDa, loading control) (B).

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