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Figure 1 | BMC Cancer

Figure 1

From: Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by Methyl-CpG binding proteins and histone modifications

Figure 1

mRNA expression of CD44, Cyclin D2, GLIPR1 and PTEN in DU145, LNCaP and MCF-7 cells. The data assessed by RT-PCR (gel electrophoretically separated on a representative agarose gel, left panel) and quantitative real-time PCR (bar charts, right panels) show the relative levels and changes in the mRNA expression of the tumour-associated genes in unstimulated basal (b), 5-aza-CdR- (A), TSA- (T) and 5-aza-CdR+TSA- (A+T) stimulated DU145, LNCaP and MCF-7 cells. The housekeeping gene β-Actin was selected as internal control. * Statistical significance of p < 0.05 according to the Fisher's exact test in respect of changes in stimulated samples compared to the basal status.

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