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Table 2 Outcome in all 5 patients who developed thrombocyte (Trc) count < 50 × 109/L after diagnosis of bone metastases

From: Anaemia and thrombocytopenia in patients with prostate cancer and bone metastases

Patient nr.

Presentation

Minimum Trc count

Time from bone metastases to Trc < 50 × 109/L

Previous systemic therapy

Outcome after Trc < 50 × 109/L

1

Synchronous

15 × 109/L

18 months

END, ZA, TAX, MITO

Died after 4 weeks, cause unknown

2

Synchronous

19 × 109/L

16 months

END, ZA, TAX

Died from haematuria and kidney failure after 8 weeks

3

Synchronous

20 × 109/L

27 months

END, ZA, TAX

Developed subdural haematoma but died from sepsis after 4 months

4

Synchronous

26 × 109/L

4 months

END, ZA

Died from surgery complications (for pathol. fracture) after 3 weeks

5

Metachronous

30 × 109/L

9 months

END, ZA

Died from subdural haematoma after 3 weeks

  1. END: endocrine therapy, ZA: zoledronic acid, TAX: taxotere, MITO: mitoxantrone