Genotypes | Number of patients (%) | Crude OR (95% CI) | P-valuea | Adjusted OR (95% CI)b | P-value | |
---|---|---|---|---|---|---|
Clinical tumor size | T1-T2 | T3-T4 | Â | Â | Â | Â |
CC | 117 (48.75) | 51 (33.55) | 1 | Â | 1 | Â |
CT | 89 (37.08) | 62 (40.79) | 1.60 [0.98-2.61] | 0.04 | 1.73 [1.01-2.76] | 0.03 |
TT | 34 (14.17) | 39 (25.66) | 2.63 [1.44-4.82] | 0.0006 | 2.89 [1.64-5.06] | 0.0004 |
Alleles | Â | Â | Â | Â | Â | Â |
C-allele | 323 (67.29) | 164 (53.95) | Â | Â | Â | Â |
T-allele | 157 (32.71) | 140 (46.05) | 1.76 [1.29-2.39] | 0.0001 | 1.98 [1.47-2.56] | 0.0001 |
Lymph nodes status | Negative | Positive | Â | Â | Â | Â |
CC | 94 (51.93) | 81 (38.39) | 1 | Â | 1 | Â |
CT | 69 (38.12) | 89 (42.18) | 1.50 [0.95-2.36] | 0.06 | 1.45 [0.98-2.27] | 0.07 |
TT | 18 (9.95) | 41 (19.43) | 2.64 [1.35-5.21] | 0.002 | 2.72 [1.44-5.43] | 0.001 |
Alleles | Â | Â | Â | Â | Â | Â |
C-allele | 257 (70.99) | 251 (59.48) | Â | Â | Â | Â |
T-allele | 105 (29.01) | 171 (40.52) | 1.67 [1.22-2.27] | 0.0007 | 1.83 [1.32-2.46] | 0.0008 |
SBR grading | 1-2 | 3 | Â | Â | Â | Â |
CC | 91 (44.39) | 63 (38.18) | 1 | Â | 1 | Â |
CT | 85 (41.46) | 64 (38.78) | 1.09 [0.67-1.76] | 0.71 | 1.12 [0.78-1.89] | 0.65 |
TT | 29 (14.15) | 38 (23.03) | 1.89 [1.02-3.53] | 0.03 | 1.98 [1.15-3.79] | 0.02 |
Alleles | Â | Â | Â | Â | Â | Â |
C-allele | 267 (65.12) | 190 (57.58) | Â | Â | Â | Â |
T-allele | 143 (34.88) | 140 (42.42) | 1.38 [1.01-1.87] | 0.03 | 1.67 [1.08-2.03] | 0.01 |
Estrogen receptor status | Positive | Negative | Â | Â | Â | Â |
CC | 50 (30.87) | 48 (33.33) | 1 | Â | 1 | Â |
CT | 76 (46.91) | 60 (41.67) | 1.22 [0.70-2.12] | 0.46 | 1.34 [0.78-2.34] | 0.35 |
TT | 36 (22.22) | 36 (25.00) | 0.96 [0.50-1.85] | 0.89 | 0.87 [0.54-1.89] | 0.85 |
Alleles | Â | Â | Â | Â | Â | Â |
C-allele | 176 (54.32) | 156 (54.17) | Â | Â | Â | Â |
T-allele | 148 (45.68) | 132 (45.83) | 0.99 [0.71-1.38] | 0.96 | 0.95 [0.66-1.27] | 0.87 |