Skip to main content

Table 4 Association statistics for CCR2-V64I genotype for high risk HPV infection in the control group

From: CCR2-V64I polymorphism is associated with increased risk of cervical cancer but not with HPV infection or pre-cancerous lesions in African women

 

High risk HPV positive (201)

High risk HPV negative (1053)

  
 

Black 62 (31)

Mixed-ancestry 139 (69)

Black 212 (20)

Mixed-ancestry 841 (80)

Genotype-high risk HPV association, adjusted for ethnicity and smoking

Genotypes

n (%)

n (%)

n (%)

n (%)

P-value

OR (95% CI)

CCR2 G→A

     

GG

34 (55)

94 (68)

135 (64)

546 (65)

-

1

AG

27 (43)

41 (29)

74 (35)

286 (34)

0.904

0.98 (0.71-1.35)

AA

1 (2)

4 (3)

3 (1)

9 (1)

0.163

2.14 (0.73-6.25)

AG + AA

28 (45)

45 (32)

77 (36)

295 (35)

0.913

1.02 (0.74-1.40)

  1. High risk HPV positive = Positive for Hybrid Capture II HPV Test, High risk HPV negative = Negative for Hybrid Capture II HPV Test.