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Table 1 Risk of colorectal cancer according to cigarette smoking

From: Cigarette smoking, genetic polymorphisms and colorectal cancer risk: the Fukuoka Colorectal Cancer Study

 

Number (%)

  

Cigarette-years

Cases

Controls

OR (95% CI)*

OR (95% CI)†

Both sexes

    

   0

299 (43.6)

326 (41.9)

1.00 (referent)

1.00 (referent)

   1-399

117 (17.1)

201 (25.8)

0.68 (0.50-0.94)

0.65 (0.47-0.89)

   400-799

195 (28.5)

180 (23.1)

1.21 (0.88-1.68)

1.16 (0.83-1.62)

   ≥800

74 (10.8)

71 (9.1)

1.21 (0.79-1.86)

1.14 (0.73-1.77)

Men

    

   0

80 (18.8)

92 (18.8)

1.00 (referent)

1.00 (referent)

   1-399

94 (22.1)

158 (32.2)

0.73 (0.49-1.09)

0.69 (0.46-1.04)

   400-799

182 (42.7)

171 (34.9)

1.24 (0.85-1.81)

1.15 (0.78-1.71)

   ≥800

70 (16.4)

69 (14.1)

1.16 (0.72-1.87)

1.05 (0.64-1.71)

Women

    

   0

219 (84.6)

234 (81.3)

1.00 (referent)

1.00 (referent)

   1-399

23 (8.9)

43 (14.9)

0.55 (0.32-0.95)

0.48 (0.27-0.86)

   ≥400

17 (6.6)

11 (3.8)

1.59 (0.72-3.51)

1.54 (0.67-3.55)

  1. * Adjusted for sex, age, and residence area.
  2. † Adjusted for sex, age, residence area, alcohol consumption, body mass index, type of job, leisure-time physical activity and parental colorectal cancer.