Figure 1

Periostin protein expression in malignant and benign prostate tissue. Weak (a) to moderate (b) epithelial and negative (a) to weak (b) stromal periostin expression in benign prostate glands. In contrast to most cancer cases, in benign tissue with stromal periostin expression the direct periglandular area is rather negative. Some cases showed a weak periostin positivity of basal cells. Prostate cancers with negative (c), weak (d), moderate (e/f2) and strong (e inset) epithelial periostin expression. The peritumoural stroma was weakly (c), moderately (d) or strongly (f1/f2) positive.