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Table 1 Predictive value of relative mRNA expression levels for identifying high-grade gliomas

From: Differential expression of centrosomal proteins at different stages of human glioma

   Group  
mRNA Low-grade glioma (n= 11) High-grade glioma (n= 23) p-value
hNinein isoform 1 Absent 0 (0%) 1 (4.3%) 0.741
  Rare 9 (81.8%) 13 (56.5%)  
  Moderate 2 (18.2%) 8 (34.8%)  
  Abundant 0 (0%) 1 (4.3%)  
hNinein isoform 2 Absent 2 (18.2%) 0 (0%) 0.254
  Rare 7 (63.6%) 18 (78.3%)  
  Moderate 2 (18.2%) 4 (17.4%)  
  Abundant 0 (0%) 1 (4.3%)  
hNinein isoform 5 Absent 1 (9.1%) 0 (0%) 0.501
  Rare 8 (72.7%) 15 (65.2%)  
  Moderate 2 (18.2%) 7 (30.4%)  
  Abundant 0 (0%) 1 (4.3%)  
hNinein isoform 6 Absent 3 (27.3%) 14 (60.9%) 0.141
  Rare 8 (72.7%) 9 (39.1%)  
  Moderate 0 (0%) 0 (0%)  
  Abundant 0 (0%) 0 (0%)  
γ-tubulin Absent 0 (0%) 0 (0%) 0.005*
  Rare 9 (81.8%) 5 (21.7%)  
  Moderate 2 (18.2%) 14 (60.9%)  
  Abundant 0 (0%) 4 (17.4%)  
Aurora A Absent 3 (27.3%) 0 (0%) 0.030*
  Rare 8 (72.7%) 20 (87.0%)  
  Moderate 0 (0%) 3 (13.0%)  
  Abundant 0 (0%) 0 (0%)  
Aurora B Absent 3 (27.3%) 4 (17.4%) 0.653
  Rare 6 (54.5%) 16 (69.6%)  
  Moderate 2 (18.2%) 3 (13.0%)  
  Abundant 0 (0%) 0 (0%)  
Centrin 2 Absent 2 (18.2%) 1 (4.3%) 0.235
  Rare 2 (18.2%) 6 (26.1%)  
  Moderate 5 (45.5%) 15 (65.2%)  
  Abundant 2 (18.2%) 1 (4.3%)  
Centrin 3 Absent 1 (9.1%) 1 (4.3%) 0.536
  Rare 3 (27.3%) 3 (13.0%)  
  Moderate 3 (27.3%) 5 (21.7%)  
  Abundant 4 (36.4%) 14 (60.9%)  
  1. NOTE: In normal brain tissue Aurora A, Aurora B, and Centrin 2 mRNAs were absent and hNinein isoforms 1, 2, 5, and 6, γ-tubulin, and Centrin 3 mRNAs were rare.
  2. * P < 0.05 by Fisher's exact test