Micronutrients attenuate progression of prostate cancer by elevating the endogenous inhibitor of angiogenesis, Platelet Factor-4

Table 1 Candidate serum biomarkers of E/S/L-supplementation.

*PF-4
Serum obtained at the end of the study period from Lady mice receiving a standard diet alone or an E/S/L-supplemented diet were subjected to a standard biomarker discovery protocol according to Materials and Methods. Ten peptides in total were observed to be significantly deregulated with respect to their serum concentrations (Table 1, p < 0.01). Molecular weights of these peptides ranged between 2297 and 8963 Da with the majority of proteins exhibiting alkaline properties (high isoelectric point (pI)) based on their binding properties to the chromatographic resins used in their discovery.

ISSN: 1471-2407