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Table 3 Correlation of microvessel density and vascular parameters with histological type, PLAP/PAS stain and microvessel invasion in canine seminoma.

From: Canine classical seminoma: a specific malignant type with human classifications is highly correlated with tumor angiogenesis

Classification

MVD (number/1.6 mm2)

Perimeter (mm/1.6 mm2)

Area (mm2/1.6 mm2)

Normal testis

48

2.61

0.005

Histological type

Intratubular Seminoma

90.0 ± 15.6

5.6 ± 0.8

0.020 ± 0.006

 

Diffuse Seminoma

87.9 ± 18.2

7.1 ± 1.0

0.030 ± 0.011

 

Intratubular/diffuse Seminoma

136.7 ± 57.7

10.7 ± 3.3

0.043 ± 0.016

P value

0.043

0.004

0.030

PLAP/PAS stain

Classical Seminoma

149.0 ± 64.0

11.5 ± 0.2

0.050 ± 0.013

 

Spermatocytic Seminoma

91.4 ± 16.9

7.2 ± 1.4

0.028 ± 0.010

P value

0.003

0.009

0.002

Tumor cells invasion of vessels

Presence

126.1 ± 52.9

10.3 ± 3.2

0.042 ± 0.016

 

Absence

95.5 ± 37.0

6.9 ± 1.8

0.029 ± 0.012

P value

0.122

0.005

0.037

  1. Note: MVD = microvessel density