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Figure 2 | BMC Cancer

Figure 2

From: Canine classical seminoma: a specific malignant type with human classifications is highly correlated with tumor angiogenesis

Figure 2

Immunohistochemical staining with vWF to detect microvessels and tumor cells invasion into vessels in canine seminomas. A. Microvessels in canine normal testis. B. Abundant microvessels were seen in intratubular/diffuse seminoma. C. Tumor cells invasion into lymphatic vessel is confirmed (arrow). D. Tumor emboli were seen in blood vessel (arrow). vWF is stained with envision system-HRP. Scale bar = 70 μm. BV = blood vessel; LV = lymphatic vessel.

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