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Figure 4 | BMC Cancer

Figure 4

From: Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways

Figure 4

Effect of IGF-1R knockdown and/or resveratrol on proliferation of colon cancer cells in vitro. Cells were seeded in 12-well plates and transfected with IGF-1R siRNA duplexes (75 nM) or non specific siRNA (siRNA control). After 24 h of transfection, cells were treated with IGF-1 (10 nM) and/or resveratrol (150 μM) for 24 h. Cell numbers were determined using a Coulter counter. * indicates suppression or elevation (p < 0.05) by treatments compared to non specific siRNA control treatment.

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