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Figure 1 | BMC Cancer

Figure 1

From: Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways

Figure 1

Growth stimulatory and inhibitory effects of IGF-1 and resveratrol, respectively in HT-29 colon cancer cells. HT-29 cells were treated with IGF-1 (I; 10 nM) and/or resveratrol (R; 50, 100, and 150 μM) for 24, 48 and 72 h, and cell numbers were determined using a Z1 Coulter counter. Results were expressed as mean ± SE for three experiments at each time point. Mean proliferation (p < 0.05) lower than that of control treatment are indicated: a, b and c for 24, 48 and 72 h, respectively and higher (p < 0.05) than that of control are indicated: x, y and z for 24, 48 and 72 h, respectively.

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