Skip to main content

Table 2 Distribution of TP53 mutations by cancer stage and type of mutation.

From: Expression signatures of TP53 mutations in serous ovarian cancers

 

All Cancers

Stage I/II

Stage III/IV

>7 yr Surv.

<3 yr Surv

Wild Type

30

9

21

16

5

Missense

40

16

24

5

19

Null

19

15

4*

2

2

Total Mutations

59 (66.3%)

31 (77.5%)

28 (57%)

7 (30.4%)

21 (80.8%)**

  1. * Null mutations as a fraction of total cases in early versus advanced cancers, p = 0.003
  2. ** Mutation rate in short versus long term survivors, p = 0.0004
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us