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Table 4 Subgroup analysis by TNM stage, tumor site and histological type for the MTHFR C677T polymorphisms.

From: Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer in a Korean population

 

CT vs CC*

TT vs CC*

 

ORa (95%CI)

ORa (95%CI)

Gastric cancer

  

TNM stage

  

I+II

0.810(0.685-0.958)

0.933(0.750-1.161)

III+IV

0.844(0.685-1.040)

0.792(0.597-1.050)

Tumor site

  

Cardiac

0.906(0.569-1.442)

0.967(0.531-1.760)

Non-cardiac

0.811(0.696-0.944)

0.876(0.717-1.070)

Histological type

  

Intestinal

0.815(0.680-0.978)

0.865(0.681-1.099)

Diffuse

0.832(0.672-1.031)

0.868(0.654-1.153)

Mixed

0.827(0.600-1.139)

1.111(0.748-1.652)

Colorectal cancer

  

TNM stage

  

I+II

0.947(0.775-1.158)

0.854(0.652-1.119)

III+IV

0.823(0.679-0.997)

0.667(0.510-0.871)

Tumor site

  

Colon

0.942(0.744-1.146)

0.727(0.553-0.952)

Rectum

0.888(0.636-1.073)

0.855(0.666-1.099)

  1. ORa, adjusted for age and sex; CC*, CC as reference group
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BMC Cancer

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