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Table 1 Clinicopathological characteristics of patients with non-small cell lung cancer (n = 99)

From: The number and microlocalization of tumor-associated immune cells are associated with patient's survival time in non-small cell lung cancer

Variable N = 99 5-yr survival (%)
Age years median (range) 60 ( 37 - 80) Overall
Gender (male: female) 80:19 32
Tumor stage:   
   I 35 49
   II 20 35
   III 34 19
   IV 10 10
Histology   
   Adenocarcinoma 45 22
   Squamous cell carcinoma 51 41
   Large cell carcinoma 3 33
Tumor grade   
   Well differentiation 3 67
   Moderate differentiation 48 40
   Poor differentiation 29 24
   Not recorded 19 20
Lymph node metastasis   
   No 59 44
   Yes 40 15
  1. Histological criteria for the tumor grading:
  2. Adenocarcinomas:
  3. Well differentiation: glandular lumens are large and similar in sizes, with less cytologic atypia.
  4. Moderate differentiation: glandular lumens vary in sizes, with obvious cytologic atypia.
  5. Poor differentiation: glandular lumens are small or absent, with obvious cytologic atypia and mitosis.
  6. Squamous cell carcinomas:
  7. Well differentiation: ≥ 20% of the tumor islets has pearl formation.
  8. Moderate differentiation: < 20% of the tumor islets has pearl formation.
  9. Poor differentiation: no pearl formation in the tumor islets; only shows intracellular keratinization.
  10. Large cell carcinomas: by definition, are poorly differentiated tumors that lack the cytologic and architectural features of small cell carcinoma, squamous cell carcinoma, or adenocarcinoma.