From: Chordoma: clinical characteristics, management and prognosis of a case series of 25 patients
Patient characteristics | Â | Â | No. (%) |
---|---|---|---|
Total number | Â | Â | 25 |
Gender | Male | Â | 18 (72) |
 | Female |  | 7 (18) |
Age (years) | Median: 62 | Â | Â |
 | Range: 40-77 |  |  |
Primary tumor site | Sacrum | Â | 11(44) |
 | Spine |  | 13(52) |
 | Skull base |  | 1 (4) |
Extension of disease | Primary disease | Â | 6 (24) |
 | Local residual/recurrent disease | 14 (56) | |
 | Metastasis |  | 5 (20) |
Treatments | Primary surgery 22 (88) | Wide margins | 5 (23) |
 |  | Intralesional margins | 17 (77) |
 | Surgery for recurrent disease |  | 13 (52) |
 | Radiotherapy 11 (44) | Adjuvant | 3 (27) |
 |  | Palliative | 8 (73) |
 | Target therapy 16 (64) | imatinib meysilate | 16 |
 |  | nilotinib | 1 |
 |  | sirolimus | 1 |
 | Chemotherapy plus target therapy |  | 1 |