Skip to main content
Figure 1 | BMC Cancer

Figure 1

From: Bilateral downregulation of Nav1.8 in dorsal root ganglia of rats with bone cancer pain induced by inoculation with Walker 256 breast tumor cells

Figure 1

Time course of pain-related behavior in rats of the Walker 256 group (n = 10), the sham group (n = 10) and the normal group (n = 8). (A) The ambulatory score increased on days 10, 14, 17 and 21 after intra-tibial injection of Walker 256 carcinoma cells but not after injection of heat-killed cells. Data are expressed as mean ± SD. **P < 0.01 compared to normal rats. (B) After Walker 256 carcinoma cell inoculation, the PWT for the inoculated hind paw progressively decreased as revealed by electronic Von Frey filament stimulus. Data are mean ± SD. **P < 0.01 compared to normal rats. (C) The PWT for the contralateral hind paw of tumor-bearing rats changed slightly but significantly on days 17 and 21 Data are expressed as mean ± SD. **P < 0.01 (ANOVA) compared to normal rats.

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us