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Table 5 Associations of total antioxidant index and macronutrients with glioma survival, stratified by histology group

From: Daily intake of antioxidants in relation to survival among adult patients diagnosed with malignant glioma

Nutrient (unit) Tertiles All or self-report (SR) only Grade II Grade III Grade IV
  Lower limit   Upper limit   (143 cases, 72 deaths) (130 cases, 103 deaths) (475 cases, 473 deaths)
      HR 95% CI HR 95% CI HR 95% CI
Antioxidant index        
T1: 50.1 to 1961.9 ALL 1   1   1  
T2: 1963.2 to 3263.0   1.34 (0.70-2.54) 1.31 (0.78-2.18) 1.02 (0.78-1.32)
T3: 3266.1 to 13512.6   0.67 (0.30-1.47) 1.04 (0.58-1.88) 0.36* (1.02-1.81)
T1: 50.1 to 1961.9 SR 1   1   1  
T2: 1963.2 to 3263.0   1.41 (0.71-2.80) 1.36 (0.62-2.94) 1.18 (0.82-1.68)
T3: 3266.1 to 13512.6   0.74 (0.31-1.77) 1.03 (0.49-2.16) 1.07 (0.72-1.59)
Total Protein (g)        
T1: 11.4 to 49.5 ALL 1   1   1  
T2: 49.6 to 70.8   0.44* (0.20-0.95) 1.44 (0.75-2.74) 1.08 (0.83-1.40)
T3: 71.1 to 241.5   0.32 (0.10-1.04) 1.73 (0.78-3.83) 0.64* (0.43-0.95)
T1: 11.4 to 49.5 SR 1   1   1  
T2: 49.6 to 70.8   0.40* (0.18-0.93) 1.57 (0.74-3.31) 1.13 (0.78-1.62)
T3: 71.1 to 241.5   0.53 (0.15-1.81) 1.18 (0.42-3.27) 0.88 (0.52-1.50)
Total Fat (g)        
T1: 10.2 to 47.1 ALL 1   1   1  
T2: 47.2 to 72.7   1.33 (0.60-2.96) 0.77 (0.43-1.38) 1.13 (0.87-1.47)
T3: 72.9 to 213.0   0.88 (0.29-2.66) 0.73 (0.35-1.51) 1.10 (0.74-1.63)
T1: 10.2 to 47.1 SR 1   1   1  
T2: 47.2 to 72.7   1.10 (0.47-2.54) 0.67 (0.29-1.53) 1.06 (0.73-1.53)
T3: 72.9 to 213.0   0.81 (0.26-2.53) 0.74 (0.30-1.85) 1.11 (0.61-2.01)
Total Cholesterol (mg)        
T1: 17.2 to 166.1 ALL 1   1   1  
T2: 166.2 to 272.7   0.53 (0.24-1.14) 0.86 (0.49-1.49) 1.50* (1.17-1.93)
T3: 273.0 to 1322.0   0.76 (0.31-1.86) 0.49* (0.25-0.95) 1.31 (0.97-1.78)
T1: 17.2 to 166.1 SR 1   1   1  
T2: 166.2 to 272.7   0.59 (0.25-1.41) 1.04 (0.53-2.03) 1.39 (0.98-1.97)
T3: 273.0 to 1322.0   1.00 (0.38-2.59) 0.68 (0.28-1.63) 1.13 (0.71-1.80)
  1. adjusted for reporting status (all cases vs self reported cases only), age at diagnosis (<48,48-65,>65), treatment (radiation, chemo, surgery - yes/no), education (<12, 12, >12), marital status (yes/no), total calories (continuous), pack years (median = 18.5), and age at first alcoholic drink (<18,18-20,>20).
  2. * p < 0.05