|
Nutrient (unit) Tertiles
|
All or self-report (SR) only
|
Grade II
|
Grade III
|
Grade IV
|
|---|
| | | | | |
(143 cases, 72 deaths)
|
(130 cases, 103 deaths)
|
(475 cases, 473 deaths)
|
|---|
| |
Lower limit
| |
Upper limit
| |
HR
|
95% CI
|
HR
|
95% CI
|
HR
|
95% CI
|
|
Vitamin C (mg)
| | | | | | | |
|
T1:
|
4.5
|
to
|
84.1
|
ALL
|
1
| |
1
| |
1
| |
|
T2:
|
84.1
|
to
|
149.6
| |
1.33
|
(0.72-2.48)
|
0.71
|
(0.40-1.27)
|
1.23
|
(0.96-1.57)
|
|
T3:
|
149.6
|
to
|
869.6
| |
0.52
|
(0.23-1.20)
|
1.07
|
(0.56-2.03)
|
.44*
|
(1.09-1.91)
|
|
T1:
|
4.5
|
to
|
84.1
|
SR
|
1
| |
1
| |
1
| |
|
T2:
|
84.1
|
to
|
149.6
| |
1.21
|
(0.63-2.34)
|
1.04
|
(0.50-2.16)
|
1.2
|
(0.84-1.72)
|
|
T3:
|
149.6
|
to
|
869.6
| |
0.56
|
(0.21-1.47)
|
1.18
|
(0.51-2.75)
|
1.28
|
(0.87-1.90)
|
|
Formononetin (mcg)
| | | | | | | |
|
T1:
|
0.1
|
to
|
9.3
|
ALL
|
1
| |
1
| |
1
| |
|
T2:
|
9.4
|
to
|
23.0
| |
1.08
|
(0.55-2.15)
|
47*
|
(0.25-0.89)
|
.27*
|
(1.00-1.61)
|
|
T3:
|
23.1
|
to
|
155.6
| |
1.08
|
(0.46-2.52)
|
0.79
|
(0.43-1.43)
|
1.04
|
(0.79-1.37)
|
|
T1:
|
0.1
|
to
|
9.3
|
SR
|
1
| |
1
| |
1
| |
|
T2:
|
9.4
|
to
|
23.0
| |
1.18
|
(0.57-2.42)
|
0.67
|
(0.29-1.53)
|
1.16
|
(0.82-1.63)
|
|
T3:
|
23.1
|
to
|
155.6
| |
0.96
|
(0.41-2.29)
|
0.56
|
(0.27-1.14)
|
1.03
|
(0.71-1.49)
|
|
Genistein (mcg)
| | | | | | | |
|
T1:
|
8.1
|
to
|
141.3
|
ALL
|
1
| |
1
| |
1
| |
|
T2:
|
141.7
|
to
|
291.3
| |
1.18
|
(0.57-2.43)
|
1.18
|
(0.66-2.12)
|
1.2
|
(0.92-1.56)
|
|
T3:
|
291.6
|
to
|
44265.2
| |
1.05
|
(0.40-2.74)
|
1.25
|
(0.69-2.27)
|
1.35*
|
(1.00-1.81)
|
|
T1:
|
8.1
|
to
|
141.3
|
SR
|
1
| |
1
| |
1
| |
|
T2:
|
141.7
|
to
|
291.3
| |
0.93
|
(0.42-2.07)
|
1.53
|
(0.71-3.29)
|
1.02
|
(0.70-1.48)
|
|
T3:
|
291.6
|
to
|
44265.2
| |
0.78
|
(0.29-2.15)
|
1.56
|
(0.65-3.74)
|
1.42
|
(0.96-2.10)
|
|
Daidzein (mcg)
| | | | | | | |
|
T1:
|
10.1
|
to
|
269.0
|
ALL
|
1
| |
1
| |
1
| |
|
T2:
|
270.1
|
to
|
440.6
| |
1.77
|
(0.96-3.26)
|
0.71
|
(0.40-1.28)
|
1.06
|
(0.83-1.36)
|
|
T3:
|
440.6
|
to
|
36886.6
| |
1.7
|
(0.70-4.14)
|
1.01
|
(0.55-1.85)
|
1.13
|
(0.86-1.49)
|
|
T1:
|
10.1
|
to
|
269.0
|
SR
|
1
| |
1
| |
1
| |
|
T2:
|
270.1
|
to
|
440.6
| |
1.54
|
(0.75-3.17)
|
1.05
|
(0.49-2.25)
|
1.2
|
(0.84-1.72)
|
|
T3:
|
440.6
|
to
|
36886.6
| |
1.21
|
(0.46-3.20)
|
0.7
|
(0.29-1.66)
|
1.08
|
(0.75-1.57)
|
|
Biochanin A (mcg)
| | | | | | | |
|
T1:
|
0.0
|
to
|
15.4
|
ALL
|
1
| |
1
| |
1
| |
|
T2:
|
15.4
|
to
|
37.8
| |
1.03
|
(0.53-2.01)
|
0.84
|
(0.47-1.51)
|
1.27
|
(0.99-1.62)
|
|
T3:
|
37.8
|
to
|
334.7
| |
0.6
|
(0.28-1.30)
|
0.91
|
(0.45-1.88)
|
1.26
|
(0.97-1.64)
|
|
T1:
|
0.0
|
to
|
15.4
|
SR
|
1
| |
1
| |
1
| |
|
T2:
|
15.4
|
to
|
37.8
| |
1.24
|
(0.62-2.49)
|
0.56
|
(0.26-1.20)
|
0.92
|
(0.64-1.33)
|
|
T3:
|
37.8
|
to
|
334.7
| |
0.56
|
(0.24-1.32)
|
0.66
|
(0.27-1.57)
|
1.02
|
(0.70-1.50)
|
|
Calcium (mg)
| | | | | | | |
|
T1:
|
85.0
|
to
|
499.9
|
ALL
|
1
| |
1
| |
1
| |
|
T2:
|
501.6
|
to
|
807.7
| |
1.23
|
(0.61-2.47)
|
0.7
|
(0.39-1.24)
|
1.06
|
(0.82-1.37)
|
|
T3:
|
808.1
|
to
|
2686.8
| |
0.95
|
(0.35-2.53)
|
1.22
|
(0.59-2.55)
|
0.87
|
(0.64-1.19)
|
|
T1:
|
85.0
|
to
|
499.9
|
SR
|
1
| |
1
| |
1
| |
|
T2:
|
501.6
|
to
|
807.7
| |
1.5
|
(0.70-3.24)
|
1.32
|
(0.65-2.67)
|
1.06
|
(0.74-1.52)
|
|
T3:
|
808.1
|
to
|
2686.8
| |
1.56
|
(0.58-4.15)
|
2.27
|
(0.93-5.53)
|
0.81
|
(0.53-1.24)
|
|
Folate (mcg)
| | | | | | | |
|
T1:
|
56.5
|
to
|
297.0
|
ALL
|
1
| |
1
| |
1
| |
|
T2:
|
297.4
|
to
|
434.7
| |
0.45*
|
(0.20-0.99)
|
1.05
|
(0.62-1.78)
|
0.84
|
(0.65-1.09)
|
|
T3:
|
435.1
|
to
|
1530.0
| |
0.35
|
(0.12-1.01)
|
0.59
|
(0.28-1.24)
|
1.08
|
(0.78-1.50)
|
|
T1:
|
56.5
|
to
|
297.0
|
SR
|
1
| |
1
| |
1
| |
|
T2:
|
297.4
|
to
|
434.7
| |
0.49
|
(0.22-1.12)
|
1.29
|
(0.61-2.73)
|
0.82
|
(0.57-1.17)
|
|
T3:
|
435.1
|
to
|
1530.0
| |
0.41
|
(0.13-1.29)
|
2.26
|
(0.77-6.60)
|
1.09
|
(0.68-1.74)
|
-
† adjusted for reporting status (all cases vs self reported cases only), age at diagnosis (<48,48-65,>65), treatment (radiation, chemo, surgery - yes/no), education (<12, 12, >12), marital status (yes/no), total calories (continuous), pack years (median=18.5), and age at first alcoholic drink (<18,18 - 20,>20).
- * p < 0.05
