Figure 2From: Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine GF treatment increased the nuclear accumulation of p53 and p21. MCF-7 cells were incubated with different concentrations of GF (15-90 μM) for 48 hours, fixed and processed to visualize either (A) p53 (red) and DNA (blue) or (B) p21 (red) and DNA (blue). Bar equals to 20 μm.Back to article page