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Table 4 Multivariate analysis on OS and DFS in 143 colorectal cancer patients

From: Clinical significance of preoperative serum vascular endothelial growth factor, interleukin-6, and C-reactive protein level in colorectal cancer

 

DFS

OS

 

HR

95% C.I

p

HR

95% C.I

p

VEGF, <825 vs. ≥825 pg/mL*

1.281

0.41-4.03

0.672

4.779

1.15-19.94

0.032

IL-6, <11.68 vs. ≥11.68 pg/mL*

1.284

0.44-3.73

0.646

1.391

0.36-5.44

0.634

CRP, <0.18 vs. ≥0.18 mg/dL*

1.030

0.38-2.80

0.954

0.869

0.22-3.51

0.844

CEA, <5 vs. ≥5 ng/mL

8.391

2.51-28.07

0.001

7.981

1.44-44.10

0.012

Tumor size, <5 vs. ≥5 cm

0.210

0.06-0.81

0.023

3.448

0.29-41.06

0.327

T, T1 vs. T2 vs. T3 vs. T4

2.479

0.94-6.57

0.068

5.963

0.76-46.87

0.090

N, N0 vs. N1 vs. N2

4.807

2.38-9.72

<0.001

5.867

2.86-86.20

0.002

Stage, I vs. II vs. III

0.783

0.12-5.10

0.798

0.042

0.00-0.67

0.025

Age, <60 vs. ≥60

0.726

0.20-2.59

0.622

11.91

2.14-66.33

0.005

  1. * cutoff value by ROC curve