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Table 3 Summary of the chromosomal aberrations found in adenocarcinomas from DMH-induced rats.

From: Gene expression profile and genomic alterations in colonic tumours induced by 1,2-dimethylhydrazine (DMH) in rats

Tumour

Aberration

Chromosome

Aberration length (kb)

Genes in the aberrant region

# 3

Amplification

1q22

109.8

Pcsk

 

Amplification

7q11

2135.3

Sirt6, Tle2, Aes, Gna11, Gna15, Ncln, NF1-C2, Tbxa2r, Pip5k1c, Apba3, Matk, Atcay_predicted, Dapk3, Zbtb7a, Map2k2, Creb3l3, Thop1, Sgta, Slc39a3, Gng7, Gadd45b, Tmprss9_predicted, RGD1308556, Sf3a2, Mknk2, Csnk1 g2, Scamp4, RGD1359682, Tcfe2a, Reep6, Pcsk4, Dazap1, Cirbp, Abca7, Grin3b, Prtn3_predicted, Prg-2, Ptbp1, Palm, Fstl3, Rnf126, Hcn2, Bsg,

# 5

Deletion

7q13

671.9

Nudt4, Ac1-114

 

Amplification

2q23

66.9

LOC360689

# 6

Amplification

15q22

189.4

Unknown

# 9

Deletion

18 p11-12

1362.1

Apc, Brd8, Gfra3, Egr1, Etf1, Catna1, Sil1