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Table 1 List of the first 25 genes up- and down-regulated in tumours.

From: Gene expression profile and genomic alterations in colonic tumours induced by 1,2-dimethylhydrazine (DMH) in rats

Gene name

Gene Description [Accession number]

FC

Up-regulated

  

Defcr4

Defensin related cryptdin 4 [NM_001013053]

183.2

Slc30a2

Solute carrier family 30 (zinc transporter), member 2 [NM_012890]

71.7

Lum

Lumican [NM_031050]

70.0

Mmp12

Matrix metallopeptidase 12 [NM_053963]

65.1

Iggc

Immunoglobulin gamma2a constant region [DQ402472]

58.8

Hoxd13_predicted

Homeo box D13 (predicted) [XM_221511]

50.5

Igfbp5

Insulin-like growth factor binding protein 5 [BC087030]

48.4

CB548350

Tenascin C [CB548350]

47.0

Msr2_predicted

Macrophage scavenger receptor 2 (predicted) [XM_227485]

45.7

Mx2

Myxovirus (influenza virus) resistance 2 [NM_134350]

43.9

Aldh1a3

Aldehyde dehydrogenase family 1, subfamily A3 [NM_153300]

42.8

Cxcl2

Chemokine (C-X-C motif) ligand 2 [NM_053647]

39.9

Mmp7

Matrix metallopeptidase 7 [NM_012864]

39.4

Nos2

Nitric oxide synthase 2, inducible [NM_012611]

38.1

S100a8

S100 calcium binding protein A8 (calgranulin A) [NM_053822]

36.2

Igfbp7

Insulin-like growth factor binding protein 7 [XM_214014]

35.8

Col12a1

PREDICTED: procollagen, type XII, alpha 1 [XM_243912]

35.7

Plod2

Procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 [NM_175869]

33.4

S100a9

S100 calcium binding protein A9 (calgranulin B) [NM_053587]

31.9

Ctgf

Connective tissue growth factor [NM_022266]

31.5

Fn1

Fibronectin 1 [NM_019143]

31.4

T_predicted

T, brachyury homolog (mouse) (predicted) [XM_217890]

30.0

Sparc

Secreted acidic cysteine rich glycoprotein [NM_012656]

29.6

Cyp26b1

Cytochrome P450, family 26, subfamily b, polypeptide 1 [NM_181087]

29.4

Nkd1_predicted

Naked cuticle 1 homolog (Drosophila) (predicted) [XM_001066780]

29.1

Down-regulated

  

Slc26a3

Solute carrier family 26, member 3 [NM_053755]

-502.6

Mptx

Mucosal pentraxin [NM_001037642]

-376.5

Retnla

Resistin like alpha [NM_053333]

-166.9

Zg16

Zymogen granule protein 16 [NM_134409]

-105.3

Clca3_predicted

Chloride channel calcium activated 3 (predicted) [XM_217689]

-99.1

Grap

GRB2-related adaptor protein [NM_001025749]

-95.2

Fabp1

Fatty acid binding protein 1, liver [NM_012556]

-94.7

Ceacam20_predicted

CEA-related cell adhesion molecule 20 (predicted) [XM_218430]

-92.8

Dpep1

Dipeptidase 1 (renal) [NM_053591]

-90.9

Pbp2

Phosphatidylethanlomine binding protein 2 [XM_575702]

-90.4

B4 galt2_predicted

UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 2 (predicted) [XM_242992]

-90.0

Apoa1

Apolipoprotein A-I [NM_012738]

-80.6

Olr1611_predicted

Olfactory receptor 1611 (predicted) [XM_223954]

-80.5

Dmbt1

PREDICTED: deleted in malignant brain tumours 1 (Dmbt1), [XM_577842]

-80.0

Muc2

Mucin 2 [U07615]

-78.7

Trpm5_predicted

Transient receptor potential cation channel, subfamily M, member 5 (predicted) [XM_344979]

-73.1

Chia

Rattus norvegicus chitinase, acidic [NM_207586]

-72.7

Kb15

Type II keratin Kb15 [XM_345877]

-72.6

Gpr156

G protein-coupled receptor 156 [NM_153295]

-71.8

Pdha2

Pyruvate dehydrogenase E1 alpha 2 [NM_053994]

-71.3

Hspa1l_mapped

Heat shock 70 kD protein 1-like (mapped) [NM_212546]

-71.0

Pcdhb13

PREDICTED: Protocadherin beta 13 [XM_001055698]

-71.0

Pcsk4

Proprotein convertase subtilisin/kexin type 4 [NM_133559]

-70.4

Masp1

Mannan-binding lectin serine peptidase 1 [NM_022257]

-70.4

C1ql1_predicted

Complement component 1, q subcomponent-like 1 (predicted) [XM_343971]

-70.3