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Table 1 Cell death-related genes in ΔAP-2γ/EGFP- expressingN202.1A cells

From: Interference with Activator Protein-2 transcription factors leads to induction of apoptosis and an increase in chemo- and radiation-sensitivity in breast cancer cells

Accession

Symbol

Definition

FC

NM_010217

Ctgf

connective tissue growth factor (Ctgf), mRNA.

3,4

NM_008737.1

Nrp

neuropilin (Nrp), mRNA.

3,3

NM_011338

Ccl9

chemokine (C-C motif) ligand 9 (Ccl9), mRNA.

3,3

NM_015786

Hist1h1c

histone 1, H1c (Hist1h1c), mRNA.

3,1

NM_009160.1

Sftpd

surfactant associated protein D (Sftpd), mRNA.

2,9

NM_008046.1

Fst

follistatin (Fst), mRNA.

2,6

AK031617

Csnk2a1-rs3

casein kinase II, alpha 1 related sequence 3, mRNA

2,5

NM_010762.2

Mal

myelin and lymphocyte protein, T-cell differentiation protein (Mal), mRNA.

2,5

NM_009397.2

Tnfaip3

tumor necrosis factor, alpha-induced protein 3 (Tnfaip3), mRNA.

2,5

NM_011580.1

Thbs1

thrombospondin 1 (Thbs1), mRNA.

2,3

NM_144516.1

Zmynd11

zinc finger, MYND domain containing 11, mRNA

2,3

NM_080428

Fbxw7

F-box and WD-40 domain protein 7, archipelago homolog (Drosophila) (Fbxw7), mRNA.

2,2

NM_145452

Rasa1

RAS p21 protein activator 1 (Rasa1), mRNA.

2,1

NM_133853.1

Magi3

membrane associated guanlylate kinase, WW and PDZ domain containig 3

2,0

NM_133738

Antxr2

anthrax toxin receptor 2, mRNA

2,0

NM_028390.1

Anln

anillin, actin binding protein (scraps homolog, Drosophila) (Anln), mRNA.

1,9

NM_012019.2

Pdcd8

programmed cell death 8 (Pdcd8), mRNA.

1,9

NM_013822.2

Jag1

jagged 1 (Jag1), mRNA.

1,8

NM_010789.1

Meis1

myeloid ecotropic viral integration site 1 (Meis1), mRNA.

1,7

J05277.1

Hk1

hexokinase mRNA, complete cds.

-2,0

NM_177089.3

Tacc1

Transforming, acidic coiled coil protein 1

-2,0

NM_010777.1

Mbp

myelin basic protein (Mbp), mRNA.

2,5

XM_483957

Dyrk2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2, mRNA

2,5

NM_018781

Egr3

early growth response 3 (Egr3), mRNA.

-2,7

NM_009153.1

Sema3b

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B (Sema3b), mRNA.

-2,9

  1. Microarray analysis (Illumina Ref-8 BeadChip) was performed on ΔAP-2γ (Δ#7, Δ#15) or EGFP- (Co#5, Co#11) expressing N202.1A clones in triplicate and 25 modulated genes involved in cell death (6 decreased, 19 increased, see Methods) were found. FC = Fold change. p < 0.001; FC. +/- 1.5.