Table 5 Risk of esophageal cancer associated with HPV infection according to gender, age, tobacco and alcohol use, and tumor stage
| Â | Â | HPV(-) No.(%) | HPV(+) No.(%) | Unadjusted OR (95% CI) | Adjusted OR (95% CI)* | ||
|---|---|---|---|---|---|---|---|
Age | ≤60 | 121(63.4) | 141(57.8) | 1.00 |  | 1.00 |  |
| Â | > 60 | 70(36.6) | 103(42.2) | 1.26 | (0.86-1.86) | 1.17 | (0.78-1.75) |
Gender | Female | 63(33.0) | 65(26.6) | 1.00 | Â | 1.00 | Â |
| Â | Male | 128(67.0) | 179(73.4) | 1.36 | (0.90-2.05) | 1.06 | (0.64-1.75) |
Tobacco†| No | 104(55.3) | 111(45.7) | 1.00 |  | 1.00 |  |
|  | Yes | 84(44.7) | 132(54.3) | 1.47‡ | (1.00-2.16) | 1.08 | (0.64-1.80) |
Alcohol††| No | 143(76.5) | 151(62.9) | 1.00 |  | 1.00 |  |
|  | Yes | 44(23.5) | 89(37.1) | 1.92‡‡ | (1.25-2.94) | 1.69‡ | (1.01-2.83) |
TNM stage | I | 20(10.5) | 39(16.0) | 1.00 | Â | 1.00 | Â |
| Â | IIa | 77(40.3) | 95(38.9) | 0.63 | (0.34-1.17) | 0.68 | (0.36-1.28) |
| Â | IIb | 59(30.9) | 59(24.2) | 0.51 | (0.27-0.98) | 0.58 | (0.30-1.14) |
| Â | III | 35(18.3) | 51(20.9) | 0.75 | (0.38-1.49) | 0.74 | (0.36-1.50) |