Table 1 Patient characteristics.
Characteristics | No of patients | % | TIMP-1 negative N (%) | TIMP-1 positive N (%) | P |
|---|---|---|---|---|---|
Age | 0.34 | ||||
<50 | 47 | 28.8 | 44 (93.6) | 3 (6.4) | |
51-65 | 94 | 57.7 | 80 (85.1) | 14 (14.9) | |
> 65 | 22 | 13.5 | 19 (86.4) | 3 (12.3) | |
Median 55.2 | |||||
Range 29-70 | |||||
FIGO stage | 0.36 | ||||
I | 0 | 0 | |||
II | 26 | 15.9 | 25 (96.2) | 1 (3.8) | |
III | 123 | 75.5 | 106 (86.2) | 17 (13.8) | |
IV | 14 | 8.6 | 12 (85.7) | 2 (14.3) | |
Tumour grade | 0.32 | ||||
1 | 34 | 20.9 | 28 (82.4) | 6 (17.6) | |
2 | 49 | 30.1 | 43 (87.8) | 6 (12.2) | |
3 | 66 | 40.5 | 61 (92.4) | 5 (7.6) | |
Not graded (clear cell or metastatic biopsy/cytology only) | 14 | 8.6 | |||
Histopathologic cell type | 0.00004 | ||||
Serous | 129 | 79.1 | 119 (92.2) | 10 (7.8) | |
Endometrioid | 11 | 6.8 | 9 (81.8) | 2 (18.2) | |
Clear cell | 5 | 3.1 | 4 (80.0) | 1 (20.0) | |
Mucinous | 9 | 5.5 | 4 (44.4) | 5 (55.6) | |
Undifferentiated | 6 | 3.7 | 6 (100) | 0 (0.0) | |
Carcinosarcoma | 3 | 1.8 | 1 (33.3) | 2 (66.7) | |
Residual postoperative tumour | 0.95 | ||||
≤ 1 cm | 60 | 44.4 | 53 (88.3) | 7 (11.7) | |
> 1 cm (Unknown: 28) | 75 | 55.6 | 66 (88.0) | 9 (12.0) | |
TIMP immunostaining | |||||
Negative | 143 | 87.7 | NA | NA | NA |
Positive | 20 | 12.3 | |||
(<0.1%: 26) | |||||
(0.1-10%: 80) | |||||
(>10-25%: 30) | |||||
(>25-50%:17) | |||||
(>50%: 10) |