Figure 1
From: Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?
Lab-on-chip results of a MLH1 MSP performed on normal tissue and peripheral blood from patient ID60. Lane one contains the lab-on-chip DNA marker. Partial methylation of both normal colon mucosa (ID60N) and peripheral blood (ID60P) was observed as they show products produced by the primer pairs amplifying unmethylated (UM) and methylated (M) template DNA. Negative (Neg) and Positive (Pos) controls represent unmethylated (Neg) and methylated (Pos) controls, respectively. The first lane is a visualization of the Agilent DNA 1000 Marker 15/1500 in base pairs (bp)