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Figure 2 | BMC Cancer

Figure 2

From: Role of IAPs in prostate cancer progression: immunohistochemical study in normal and pathological (benign hyperplastic, prostatic intraepithelial neoplasia and cancer) human prostate

Figure 2

Immunohistochemical analysis. c-IAP-2 immunostaining appeared in the basal epithelial cells of normal (A) and BPH (B), whereas appeared in secretory epithelial cell of PC (C) samples. The cytoplasm of basal (normal and BPH) and secretory (cancer) epithelial cells presented positive immunoreaction to ILP in normal (D), high grade prostatic intraepithelial neoplasia (PIN) (E) and PC samples (F). No immunoreaction was found to NAIP in normal prostate (G) but was localized in the cytoplasm of epithelial cells in BPH (H) and PC (I) samples. Normal prostate (J) was negative to Survivin whereas immunoreaction was found in epithelial cells of BPH (K) and PC (L) samples. Immunoreaction to XIAP was observed in the apical cytoplasm of epithelial cells in BPH patients (Figs. M-N) whereas was perinuclear in high grade prostatic intraepithelial neoplasia (PIN) and PC (P) samples. Scale bars: 10 μm (O), 20 μm (B, E, H) and 30 μm (A, C-D, F-G, I-N, P).

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BMC Cancer

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